The FBXO5 Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to Emi1, and FBXO5. This antibody recognizes Human antigen. The FBXO5 Antibody (Center) has been validated for the following applications: ELISA, and Western Blot.
Description
This gene encodes a member of the F-box protein family
which is characterized by an approximately 40 amino acid motif, the
F-box. The F-box proteins constitute one of the four subunits of
the ubiquitin protein ligase complex called SCFs
(SKP1-cullin-F-box), which function in phosphorylation-dependent
ubiquitination. The F-box proteins are divided into 3 classes: Fbws
containing WD-40 domains, Fbls containing leucine-rich repeats, and
Fbxs containing either different protein-protein interaction
modules or no recognizable motifs. The protein encoded by this gene
belongs to the Fbxs class. This protein is similar to xenopus early
mitotic inhibitor-1 (Emi1), which is a mitotic regulator that
interacts with Cdc20 and inhibits the anaphase promoting complex.
Alternatively spliced transcript variants encoding different
isoforms have been identified